Alka-Seltzer is an effervescent antacid and pain reliever first marketed by the Dr. Miles Medicine Company of Elkhart, Indiana It was developed by head chemist Maurice Treneer. Alka-Seltzer is marketed for relief of minor aches, pains, inflammation, fever, headache, heartburn, stomachache, indigestion, and hangovers, while neutralizing excess stomach acid It was launched in 1931. A spin-off of Alka-Seltzer made to relieve colds and flu, Alka-Seltzer Plus, was later introduced. A short-lived antacid non-aspirin variant, Alka-Mints, was introduced in 1994 and discontinued in 1997. Another non-aspirin-based variant, Alka-Seltzer Gold, was later released.